SARS virus : Transmission, Virology, Symptoms and Treatment

SARS virus :-




  • SARS virus (Severe Acute Respiratory Syndrome) is viral respiratory illness caused by a coronavirus called SARS associated coronavirus (SARS-CoV).

Introduction of SARS virus :-

  • SARS coronvirus cause severe acute respiratory syndrome.
  • Family of SARS coronvirus is belongs to Coronaviridae and subfamily of this virus is corona virinae.
  • Genus of SARS coronvirus is belongs to the Betacoronavirus.
  • There are three main group of coronvirus was identified.
  1. Alphacoronvirus
  2. Betacoronvirus
  3. Gammacoronvirus

Virology of SARS virus :-

  • SARS coronavirus is a one type of positive and single stranded RNA virus.
  • Genome size of this virus is 27.9kb and this size largest among RNA virus.
  • SARS coronavirus have 13 genes and 14 proteins.
  • The function of these proteins is known as ORFs 1a and 1b bind with replicase.
  • In this virus four major structural proteins are present such as nucleocapsid, spike, membranes and envelope.

Morphology of SARS virus :-

  • The characteristics of SARS coronavirus is character of the coronavirus family as a whole.
  • SARS coronavirus have large pleomorphic spherical particles with bulbous surface projections that make a corona around particles.
  • The envelope of the SARS coronavirus consist lipid and occurs¬† to contain of a distinct pair of electron dense cells.
  • Internal structure of SARS coronavirus shell is single stranded helical ribonucleoprotin.
  • There are also long surface prediction that extend from the lipid envelope.
  • The size of particles are 80 to 85 nm.

    SARS virus
    SARS virus

Transmission or infection :-

  • Is known to transmitted mammals & birds mainly control in human.
  • And cultivated animals primarly transmit upper respiratory system in mammals and gastrointestion tract of birds.
  • SARS coronvirus formed a significant precen of the human cold.




Symptoms :-

  • Normal symptoms of SARS infection are fever, dry cough, headache, muscle ache and difficulty¬† in breathing.
  • Pain in muscles.
  • Coughing, infection and headache.
  • Respiratory distress.

Diagnosis :-




  • We can diagnosis SARS disease by using of polymerase chain reaction (PCR).
  • Polymerase chain reaction is able to detect genetic material.
  • We can also diagnosis by using of serological testing and viral culture.
  • In serological testing in we used antibodies for the detection.

Treatment :-

  • Perfect treatment of SARS disease can not found.
  • In treatment, required intensive care and observation.
  • We can control this disease in starting phase by using of such as:
  • Broad spectrum antibiotics and antiviral agents.
  • Immunomodulatory therapy.

 

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